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Cornelissen, T., Haddad, D., Wauters, F., Van Humbeeck, C., Mandemakers, W., Koentjoro, B., et al

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in turn, these mechanisms lead to melanocytes destruction (via IS stimulation) and to the impossibility of their maturation and resynthesis

both NNMT and resveratrol modulate Sirtuin 1 (Sirt1) activity 83,84 , and resveratrol 83 and 5A-1MQ increase Parasutterella abundance, suggesting a potential causal link